Chemistry Journal of Moldova

DOI: dx.doi.org/10.19261/cjm.2015.10(1).01

Graphical Abstract:  This review presents a synthetic transformations of ent-kaurane diterpenes, covering various aspects of the chemical and microbiologically transformations of native ent-kaur-16-en-19-oic acid, namely, its reactions via COOH groups, double bonds and rearrangements of the carbon skeleton, what we offer a wide range of natural and synthetic derivatives potentially biologically actives and convenient synthon for their synthesis.

DOI: dx.doi.org/10.19261/cjm.2015.10(1).08

Graphical Abstract:  The paper relates on the discovered bioactivity of the iridoid glycosides extract (IGE) from Linaria genistifolia (L.) Mill, namely its stimulating influence on the resistance of the winter wheat Odesschi 51 plant to the caused by the F. oxysporum and H. avenae pathogenic fungi root rot. 1H and 13C NMR characteristics of 5-O-allosylantirrinoside in Py-d5 are for the first time presented. Structures of two conformers of the IGE main component, 5-O-allosylantirrinoside in D2O and Py-d5 solutions are proposed, based on the experimental NMR evidence and molecular modeling studies.

DOI: dx.doi.org/10.19261/cjm.2010.05(2).07

Graphical Abstract: The paper reports on the structural elucidation of the four steroidal glycosides, where two are new, isolated from Veronica chamaedrys L. plants for the first time on the basis of extensive spectral analysis, including 2D NMR spectral data and chemical evidences.

DOI: dx.doi.org/10.19261/cjm.2010.05(2).08

Graphical Abstract: The paper describes the syntheses of new derivatives of dihydroxyfumaric acid and investigations of their antioxidant activities using the DPPH method.